MATRIX METALLOPROTEINASES: KEY PLAYERS IN TISSUE REMODELING AND DISEASE

Matrix metalloproteinases matrix MMPs (MMPs) represent a large group of zinc-dependent endopeptidases. These proteases play critical parts in {extracellulartissue matrix remodeling, contributing to physiological processes such as wound healing, embryogenesis, MMP and angiogenesis. However, dysregulation in MMP activity is associated to a wide varie